Pravachol, Pravastatin

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  1. Is your cholesterol really too high?Read the original story w/Photo

    Tuesday Jan 20 | Inside Bay Area

    There is an International Network of Cholesterol Skeptics - a group of scientists, physicians, other academicians and science writers from various countries - who offer this food for thought.

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  2. Clarithromycin-Statin Mix Can Cause Severe Adverse EventsRead the original story

    Wednesday Jan 21 | US Pharmacist

    The combination of clarithromycin with certain statins increases the risk of adverse events, which in older patients may necessitate hospitalization. Researchers at Western University examined data on more than 104,000 patients aged 66 years who took rosuvastatin, pravastatin, or fluvastatin and also had a prescription for clarithromycin or azithromycin.

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  3. Glenmark Generics Limited - Strategic SWOT Analysis Review - New Study ReleasedRead the original story

    Saturday Jan 17 | PR-inside.com

    Glenmark Generics Limited is a pharmaceutical company. The company develops, manufactures, markets and distributes generic finished dosage forms and active pharmaceutical ingredients.

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  4. Severe hepatic injury associated with different statinsRead the original story

    Tuesday Jan 13 | GastroHep.com

    A study in the most recent issue of the Journal of Gastroenterology & Hepatology investigates severe hepatic injury associated with different statins in patients with chronic liver disease. In this study, Dr Jou-Wei Lin and colleagues from Taiwan estimated the risk of severe hepatic injury associated with different statins in patients with chronic liver disease.

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  5. Low risk of statin-linked hepatic injury in liver diseaseRead the original story w/Photo

    Wednesday Jan 7 | PhysOrg Weblog

    For patients with chronic liver disease, statin initiation is associated with low overall incidence of hospitalization due to severe hepatic injury, according to a study published in the January issue of the Journal of Gastroenterology and Hepatology . Chia-Hsuin Chang, M.D., Ph.D., from the National Taiwan University in Dou-Liou City, and colleagues conducted a nationwide population-based cohort study involving 37,929 subjects with chronic liver disease who started statin therapy .

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  6. Use of cholesterol-lowering meds on the riseRead the original story w/Photo

    Dec 24, 2014 | Fox News

    The percentage of Americans taking medication to control their cholesterol has risen by a third over the past decade, a new study finds. In 2012, the percentage of people ages 40 and over who said they had used a cholesterol-lowering medication in the past month was 28 percent, up from 20 percent in 2003, according to the report from the Centers for Disease Control and Prevention.

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  7. Mixing clarithromycin with statins could lead to hospitalizationRead the original story w/Photo

    Dec 23, 2014 | Medical News Today

    The antibiotic clarithromycin and cholesterol-lowering statins are some of the most widely prescribed drugs in the world. New research, however, has found that certain combinations of the two could increase the risk of adverse events and, in certain cases, could lead to hospitalization.

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  8. Certain Antibiotic/Statin Combos May Be Unsafe MixRead the original story w/Photo

    Dec 22, 2014 | MedlinePlus

    Seniors who take the antibiotic Biaxin along with certain types of cholesterol-lowering statins are at risk for drug interaction side effects that can lead to hospitalization or even death, a new study suggests. "Physicians need to be made aware of this newly described dangerous interaction and consider alternative antibiotics to prevent toxicity that could be life-threatening," said expert Dr. Kevin Marzo, chief of cardiology at Winthrop-University Hospital in Mineola, N.Y. He was not involved in the new study, which appears in the Dec. 22 issue of the Canadian Medical Association Journal .

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  9. Use of Cholesterol-Lowering Meds on the RiseRead the original story w/Photo

    Dec 22, 2014 | LiveScience

    The percentage of Americans taking medication to control their cholesterol has risen by a third over the past decade, a new study finds. In 2012, the percentage of people ages 40 and over who said they had used a cholesterol-lowering medication in the past month was 28 percent, up from 20 percent in 2003, according to the report from the Centers for Disease Control and Prevention.

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  10. Clarithromycin Plus Certain Statins Associated with Hospitalization Risk in Older AdultsRead the original story

    Dec 22, 2014 | Journal Watch

    Using Canadian healthcare databases, researchers examined records of 100,000 patients aged 66 and older who were taking statins not metabolized by CYP3A4 and who also received a prescription for either clarithromycin or azithromycin. Clarithromycin inhibits OATP1B1 and OATP1B3, but azithromycin does not.

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  11. Statin-Antibiotic Combination Can Be DeadlyRead the original story w/Photo

    Dec 22, 2014 | News Max

    Seniors who take the antibiotic Biaxin along with certain types of cholesterol-lowering statins are at risk for drug interaction side effects that can lead to hospitalization or even death, a new study suggests. "Physicians need to be made aware of this newly described dangerous interaction and consider alternative antibiotics to prevent toxicity that could be life-threatening," said expert Dr. Kevin Marzo, chief of cardiology at Winthrop-University Hospital in Mineola, N.Y. He was not involved in the new study, which appears in the Dec. 22 issue of the Canadian Medical Association Journal .

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  12. Clarithromycin-statin mix can cause drug interactions, requiring hospitalizationRead the original story w/Photo

    Dec 22, 2014 | Science Daily

    The combination of the common antibiotic clarithromycin with some statins increases the risk of adverse events, which may require hospital admission for older people, according to a new study. Statins, used to lower cholesterol, are one of the most widely prescribed drugs, with projections estimated at more than 1 billion people around the globe.

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  13. Using Bayesian-PBPK modeling for assessment of inter-individual...Read the original story

    Dec 19, 2014 | CiteULike

    Inter-individual variability in clinical endpoints and occurrence of potentially severe adverse effects represent an enormous challenge in drug development at all phases of clinical research. To ensure patient safety it is important to identify adverse events or critical subgroups within the population as early as possible.

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  14. Early statin use may give long-term heart benefitsRead the original story w/Photo

    Dec 14, 2014 | Crescent-News.com

    Taking a cholesterol-lowering drug for five years in middle age can lower heart and death risks for decades afterward, and the benefits seem to grow over time, a landmark study finds.

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  15. Early statin use may give long-term heart benefitsRead the original story

    Nov 24, 2014 | The Star

    Taking a cholesterol-lowering drug for five years in middle age can lower heart and death risks for decades afterward, and the benefits seem to grow over time, a landmark study finds. Doctors say it's the first evidence that early use of a statin can have a legacy effect, perhaps changing someone's odds of disease for good.

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  16. Web-scale pharmacovigilance: listening to signals from the crowdRead the original story

    Nov 21, 2014 | CiteULike

    Adverse drug events cause substantial morbidity and mortality and are often discovered after a drug comes to market. We hypothesized that Internet users may provide early clues about adverse drug events via their online information-seeking.

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  17. Scottish study shows heart benefit of the use of statins earlier in lifeRead the original story w/Photo

    Nov 20, 2014 | South China Morning Post

    Taking a cholesterol-lowering drug for five years in middle age could lower heart and death risks for decades, and the benefits seemed to grow over time, a study in Scotland has found. Doctors have said it was the first evidence that early use of a statin could have a legacy effect, perhaps permanently changing someone's odds of disease.

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  18. Early statin use may give long-term heart benefitsRead the original story w/Photo

    Nov 20, 2014 | Daily Herald

    Taking a cholesterol-lowering drug for five years in middle age can lower heart and death risks for decades afterward, and the benefits seem to grow over time, a landmark study finds. Doctors say it's the first evidence that early use of a statin can have a legacy effect, perhaps changing someone's odds of disease for good.

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  19. Using statin early can help heart for decades to comeRead the original story w/Photo

    Nov 20, 2014 | The Times-Tribune

    Taking a cholesterol-lowering drug for five years in middle age can lower heart and death risks for decades afterward, and the benefits seem to grow over time, a landmark study finds. Doctors say it's the first evidence that early use of a statin can have a legacy effect, perhaps changing someone's odds of disease for good.

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  20. Use of cholesterol drug in middle age lowers heart risks for decades later, study findsRead the original story w/Photo

    Nov 19, 2014 | Canada.com

    Taking a cholesterol-lowering drug for five years in middle age can lower heart and death risks for decades afterward, and the benefits seem to grow over time, a landmark study finds. Doctors say it's the first evidence that early use of a statin can have a legacy effect, perhaps changing someone's odds of disease for good.

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