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1 hr ago | BioSpace
NLG919 is a small-molecule, orally bioavailable, immune checkpoint inhibitor designed to counteract a fundamental mechanism by which tumors evade immune-mediated destruction.
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5 hrs ago | Newswise
Duke Medicine, DURHAM, N.C. - Researchers at Duke Medicine conclude that high cholesterol may make breast cancer worse when they found that a byproduct of cholesterol functions like the hormone estrogen, leading to increases in the growth and spread of breast cancer.
9 hrs ago | Science Daily
What's more, patients must often try several different SSRI medications, each with a different set of side effects, before finding one that is effective.
13 hrs ago | Medical News
SafeBridge Consultants, Inc. , a division of Trinity Consultants, Inc., Dallas, TX, with offices in Mountain View, CA, New York, NY, and Liverpool, UK, announces the availability of computational predictive toxicology services to the biopharmaceutical and chemical industry.
Misfolded protein molecules, caused by gene mutation, are capable of maintaining their function but are misrouted within the cell and can't work normally, thus causing disease.
The study met its primary endpoint of safety, with data demonstrating treatment with ibrutinib as an initial therapy was associated with adverse events that were predominantly Grade 1 or 2 in nature.
Philadelphia, PA-Data from the National Lung Cancer Screening Trial -conducted by the American College of Radiology Imaging Network and National Cancer Institute Lung Screening Study-provided researchers the opportunity to investigate the probability that a cancer detected with screening low-dose computed tomography would not have progressed to ... (more)
ImmunoGen announces initial safety and response findings for SAR650984 ImmunoGen announced the first clinical findings with SAR650984 reported in an oral presentation at the ASH annual meeting.
Acorda Therapeutics presents new data on Diazepam nasal spray Acorda Therapeutics announced that new data from a pharmacokinetics study on Diazepam Nasal Spray found comparable pharmacokinetics whether the drug was administered during or immediately after a seizure.
This review presents a comprehensive discussion on the chemistry, pharmacokinetics, and pharmacodynamics of ifetroban sodium, a new thomboxane A2/prostaglandin H2 receptor antagonist.
The most recent issue of the Alimentary Pharmacology & Therapeutics compares the effectiveness of the hepatitis C virus protease inhibitors boceprevir vs telaprevir in a large cohort in the USA.
Older patients are particularly vulnerable to adverse drug reactions because age is associated with changes in pharmacokinetics and pharmacodynamics that may alter drug metabolism.
Dr. Eli Fischer looks like everyone's Jewish uncle; twinkling smart eyes, an instant easy smile, and a kind, caring face.
The caffeine in a cup of coffee might help your small blood vessels work better, according to research presented at the American Heart Association's Scientific Sessions 2013.
The EPA and other federal agencies have released their 2013 Strategic Sustainability Performance Plans that outline steps the agencies will take to reduce carbon emissions and save energy.
While the term pharmacometrics has become fashionable since the start of the 21st century, the methods it encompasses have evolved from early pharmacokinetics work to full-blown clinical trial simulation, thanks largely to enhanced computational capability and the work of many insightful minds.