First drug approved to treat malignant pleural mesothelioma

Three researchers who led the discovery and development of the first drug approved to treat malignant pleural mesothelioma (MPM), a cancer associated with exposure to asbestos, were named as Heroes of Chemistry by the American Chemical Society (ACS). Researchers Homer Pearce, Ph.D., Chuan (Joe) Shih, Ph.D., and Edward C. Taylor, Ph.D., led a long-standing collaboration between Eli Lilly and Company and Princeton University that resulted in the compound ALIMTA(R)(pemetrexed for injection), the first drug ever approved for the treatment of MPM. ALIMTA, in combination with cisplatin, is indicated for the treatment of patients with malignant pleural mesothelioma whose disease is unresectable or who are otherwise not candidates for curative surgery.

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