Interactions of between pathogenic agents and host become most focused subject in order to determination of exact mechanisms of pathogenesis.
TH always have important role in regulation of immune response. Recantly Treg discovery as modulator of immune response in chronic inections can appears a new scope in this disorders. However more investigations are need to complete all aspects of these manipulations in immunology and microbiology.
Amin talebi bezmin abadi
Tarbiat Modares University