No Conflict Of Interest

http://www.journals.uchicago.edu/CID/journal/...

"Potential conflicts of interest. G.P.W.[Gary Wormser] has received consulting fees from Baxter and research support from Immunetics, and he is a founder of Diaspex, a company that does not offer products or services. R.J.D.[Ray Dattwyler] has served as a speaker for Pfizer and is part owner of Biopeptides, a biotech company that develops vaccines and laboratory diagnostics, including products for Borrelia burgdorferi. J.J.H.[John Halperin] has served as an expert witness on behalf of Lymerix (GlaxoSmithKline). A.C.S.[Allen Steere] has received consulting fees from Baxter. P.J.K. has a patent pending with a university on a babesiosis diagnostic procedure that is not yet on the market. All other authors: no conflicts."

OspA- The best defense is a good offense

Allen Steere says: http://www.annals.org/cgi/content/full/121/8/... "Patient 12 had had high fever, meningeal symptoms, and subsequent arthritis in 1982. She was noted to have a positive serologic test result for Lyme disease 4 years later and was treated with 2 weeks of parenteral penicillin. She later developed a progressive speech disorder, bradykinesia, and abnormal ocular motor function. Magnetic resonance imaging of the brain showed scattered white matter lesions in the hemispheres and pons, and she was diagnosed with supranuclear palsy. Lumbar puncture showed no selective concentration of antibody in the spinal fluid. Nevertheless, she was re-treated with 2 weeks of parenteral ceftriaxone in 1989 that had no effect on her neurologic symptoms. During the time of observation, this patient died. At autopsy, lymphoid mononuclear cells were observed surrounding the intracerebral vessels in one section.*** Using Dieterle silver stain, a spirochete was present in the cortex and another was exterior to a leptomeningeal vessel."***

(One of Steere's multiply treated patients died anyway with spirochetes in her brain.)

Mark Klempner says: "Fibroblasts protected B. burgdorferi for at least 14 days of exposure to ceftriaxone. Mouse keratinocytes, HEp-2 cells, and Vero cells but not Caco-2 cells showed the same protective effect.*** Thus, several eukaryotic cell types provide the Lyme disease spirochete with a protective environment contributing to its long-term survival." ***

http://www.ncbi.nlm.nih.gov/pubmed/1634816...

3) "The chronic forms of the disease such as arthritis (joint involvement), acrodermatitis chronica atrophicans (skin involvement), and Bannwart's syndrome (neurological involvement) may last for months to years and are associated with the persistence of the spirochete. A case of maternal-fetal transmission of B. burgdorferi resulting in neonatal death has been reported. Domestic animals such as the dog also develop arthritis and lameness to this tick-borne infection. For every symptomatic infection, there is at least one asymptomatic infection. Lyme disease is presently the most commonly reported tick-borne disease in the United States." -- Russell Johnson, in the first patent for a Lyme vaccine

The patent also says:

"The infection may be treated at any time with antibiotics such as penicillin, erythromycin, tetracycline, and ceftriaxone.*** Once infection has occurred, however, the drugs may not purge the host of the spirochete but may only act to control the chronic forms of the disease. Complications such as arthritis and fatigue may continue for several years after diagnosis and treatment."***

http://patft.uspto.gov/netacgi/nph-Parser...

14) "...the specter of asymptomatic infection is something that troubles me a great deal and troubles a great number of my colleagues who need to treat Lyme disease. The obvious analogy with syphilis infection with Treponema pallidum is there to consider. It is well known that Borrelia burgdorferi indeed after asymptomatic infection can lurk or secrete itself in certain areas of the body, perhaps the central nervous system or perhaps the joint spaces, only to reappear months or maybe years later in the form of late stages of illness which are harder to diagnosis and treat."
--East Slyme's Vijay Sikand to the FDA Vaccine Committee in 1998, when trying to scare us about how serious Lyme disease is:
http://www.fda.gov/ohrms/dockets/ac/98/transc...



"Harder to diagnose and treat?" I thought Lyme was "easily diagnosed and cured?"



15) The combined National Institutes say:--
http://intramural.nimh.nih.gov/inip/call4prop... "8. Infectious diseases of the CNS mediated through immune mechanisms, including acute and chronic Lyme disease and neuroAIDS;"

http://www.ncbi.nlm.nih.gov/sites/entrez...
Antimicrob Agents Chemother.
In vivo activities of ceftriaxone and vancomycin against Borrelia spp. in the mouse brain and other sites.
Kazragis RJ, Dever LL, Jorgensen JH, Barbour AG [ <-- CDC "officer" owner of the ImmuLyme patent, over which Gary Wormser is still being sued]

Department of Medicine (Infectious Diseases), University of Texas Health Science Center at San Antonio 78284, USA.

Borrelia burgdorferi, the agent of Lyme disease, and B. turicatae, a neurotropic agent of relapsing fever, are susceptible to vancomycin in vitro, with an MIC of 0.5 microgram/ml. To determine the activity of vancomycin in vivo, particularly in the brain, we infected adult immunocompetent BALB/c and immunodeficient CB-17 scid mice with B. burgdorferi or B. turicatae. The mice were then treated with vancomycin, ceftriaxone as a positive control, or normal saline as a negative control. The effectiveness of treatment was assessed by cultures of blood and brain and other tissues. Ceftriaxone at a dose of 25 mg/kg of body weight administered every 12 h for 7 to 10 days eliminated cultivable B. burgdorferi or B. turicatae from all BALB/c or scid mice in the study. Vancomycin at 30 mg/kg administered every 12 h was effective in eliminating infection from immunodeficient mice if treatment was started within 3 days of the onset of infection. If treatment with vancomycin was delayed for 7 days or more, vancomycin failed to eradicate infection with B. burgdorferi or B. turicatae from immunodeficient mice.*** The failure of vancomycin in eradicating established infections in immunodeficient mice was associated with the persistence of viable spirochetes in the brain during antibiotic treatment.***

Dear Hartford Courant, please read the web site
www.lymecryme.com and also see the $20,000 reward.

They have spun a web of fraud and deceit about the disease at the CDC’s Dearborn, MI, Conference in 1994.
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It is very important for all of us to understand what transpired at the Dearborn Conference.
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For Gary Wormser to report in the IDSA Guidelines that one has to have a positive test for Lyme means he has published scientific fraud. Similarly, the CDC says their testing for Lyme is “valid,” when it is hardly valid, if only 15% of the cases of Lyme are identified by the Steere IgG panel.
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By showing the data at The Dearborn Conference it should make the reader understand the deceit and fraud that has been committed against mankind. It is not only inexcusable but so evil in its intent to destroy so many lives. One could only wonder if at one time they were good upstanding men and women, or just always driven by money, greed and power, not caring who they have hurt or destroyed in their wake.
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Yale, Alan Barbour (a CDC officer) et al, are the owners of many patents on Lyme, and other methods of detection here in the U.S and abroad. Yale owns a patent for a scientifically valid Lyme test, but will not let anyone use it. How can someone own a patent on a disease or method of detecting a disease? This is truly a conflict of interest. The very same people who are defining the diseases hold patents to make profits off of the sick by the selling of test kits. Why would they want us to get better when they can make more money off the sick and ailing?
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The Blumenthal antitrust has opened the eyes of many. Some activists have been put into place by higher echelons to divide the Lyme community and keep them occupied with other trivial matters. Bills were written to fail by some activist groups to keep the diversion alive. Keeping the minion active doing trivial things is a tactic used by governments worldwide.
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In the antitrust, it simply asked the IDSA to disclose their organizational paperwork. For two years, it went unanswered. Instead of disclosing their financial and vested interests, the IDSA chose to revamp their staunch 2006 guidelines. If they stood fast beside their own guidelines, why redo them? If they had nothing to protect, then why did they not just simply disclose this information? Even though they have not had one omission of guilt spring from their camp, revamping the guidelines says it all.
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Now it is very well known, the scientific fraud and intent to do harm they have deployed on us. As victims of their abuse, we can now seek retribution.
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Please see http://www.lymecryme.com , for “in their own data” lies the truth.
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So, Dr. Poretz, the best the Infectious Diseases Society has to offer is actually to do nothing at all for Lyme victims. Can't you and your colleagues understand that one round of antibiotics only kills SOME of the bacteria, not all. It reproduces and the victim becomes ill over and over. We are under no assumption that we will be cured from this dreadful disease, but antibiotics are the only RELIEF we can obtain. Talk therapy and painkillers are not going to bring us wellness, nor is denial of our relapsing illness. The IDSA philosophy is "too bad, so sad" to all Lyme victims who don't get well with one course of antibiotics. And that's why we're angry.

As a Person who has late stage Lyme disease and undergone treatment. I know first hand that a small amount of antibiotic's do not finnish the job

I know that only when I was Given 57 day's of IV Rocephen 2 gm's a day did I finnaly see a change in my condition that was the turning point .

I also have seen many other's have the same change under the same condition's

I can only come to the same conclustion that many other lyme disease people have come to from first hand Knowedge
That Lyme Disease takes at least 57 days of IV Rocephen at 2 gr's a day to cure or stop the spread of Infection .

This is First hand Knowedge over and over again. if it was not first hand knowedge from people who have the disease it would not carry the weight it does .
I know that it work's and I also know that 30 days of Doxycyclin will not and that's first hand also so they can do what they want to with there guidline's as they have never had lyme disease and anything they say is second hand at best you deciede for yourself but if I was going to make a choice for someone I love and care for I would only take first hand information because second hand is never the best

Kathleen, a little manic today aren't you? I hear Dr. Poretz plays golf with McSweegan

If the IDSA were concerned about over prescribing antibiotics, the majority of dermatologist, would have their licenses in jeopardy as do Lyme doctors who treat Lyme Disease. Who prescribes more antibiotics??? A 6-month prescription for antibiotics for acne is not uncommon. Why do so many Lyme disease patients get better after extended antibiotic therapy?

If I ever get Lyme disease I will go to a Veterinarian. A dog gets 30 days of antibiotics! A human IF they get diagnosed, they get a single dose.

And they wonder why people are upset!

According to AG Blumenthal, "IDSA's 2006 Lyme disease guideline panel undercut its credibility by allowing individuals with financial interests -- in drug companies, Lyme disease diagnostic tests, patents and consulting arrangements with insurance companies -- to exclude divergent medical evidence and opinion.� And the resulting IDSA guidelines represent "the best medical science has to offer patients with Lyme disease"? Those patients will continue to suffer as long as the tainted IDSA Lyme guidelines remain in place, and as long as Dr. Poretz continues to defend the blatant conflicts of interest within his organization.

The IDSA panel members and their colleagues actually end up making MORE revenue by denying proper treatment of lyme disease. The drug companies also make out very well. When lyme is left untreated or is treated minimally, it is my understanding that it is the germs which are left over, which have not been killed, which become antibiotic resistant.

If long term treatment is needed for specific patients and they are denied this treatment, they are then usually labeled with autoimmune disease or other unclear diagnoses. How can it be said that if a patient is sick with the same exact symptoms on the day after treatment has been stopped, that they now have a completely different disease?

I mentioned above that more revenue is made once people become chronically ill. They are shuffled from one specialist to another, many expensive tests are ordered, antidepressants and scores of other drugs are now prescribed for the many symptoms throughout the body...which the progressive stage of Lyme disease causes. Why aren't the insurance companies demanding proper long term treatment for lyme...when needed...especially with the much more afforable ORAL antibiotics. Long term treatment for Lyme does not automatically equate with IV antibiotics. Orals can work very well for many people.

Where is the science that proves what the IDSA is saying....that Lyme is cured after 3 weeks of antibiotics? Drug companies make much more money on many symptomatic treatments rather than on ones which cure.Doctors also have continued business. The testing companies are also happy. If a person is cured or their disease process is arrested, you are no longer a good customer of the drug company. Blumenthal said there were conflicts of interest. I wonder if those had anything to do with the drug companies?

The IDSA needs to begin to address 1.the issues of pleomorphism 2. different strains of the lyme spirochete which are NOT being tested for 3. the idea that antibiotic resistance developes when an antibiotic is not used long enough to kill all of the germs and the remaining ones become resistent. 4 The IDSA needs to address the MANY scientifuc reasons as to why patients can test negative and still have a chronic relapsing infection.
5. How can the IDSA justify their position with all the clinical evidence,the scientific evidence AND patient experience which points directly to chronic infection?

We are not just going to take your word for it. Show us your proof.Lyme is becoming a global scourge and millions of lives hinge upon your rash statement that lyme is almost always cured within a month.

Where are the public debates? Why is the evidence that shows lyme is a chronic relapsing brain infection being kept from the public and the medical community? How can the IDSA totally discount the evidence of persistent infrection...especially when they have no proof of their own for their claim that lyme is not chronic or relapsing? Negative tests are not adequate proof as testing is very unreliable.

The scientific community is studying the Lyme disease microbe as a potential biowarfare agent.....as a disabling agent.This is an admitted fact. Are we being denied treatment so that a biowarfare agent can be allowed to pass quietly through the population? It has been stated in government biowarfare documents that disabling agents are much more effective in bringing down a country than are biological agents which kill. We have been told that disabling agents also tie up others in the communities in caring for the sick. Eventually, if allowed to spread untreated, this situation could cause economic collapse.

If the "treatment" guidelines put out by the IDSA have the potential to affect literally millions of lives....then I think we need to display the evidence of both sides and then we can see where the real truth lies.

Part two on IDSA www.lymecryme.com
In a New England Journal of Medicine study, Drs. Dattwyler and John Halperin (also of the IDSA) "studied 17 patients who had presented with acute Lyme disease and received prompt treatment with oral antibiotics, but in whom chronic Lyme disease subsequently developed."
These "chronic Lyme" patients tested negative on currently-available blood tests: "Although these patients had clinically active disease, none had diagnostic levels of antibodies to B. burgdorferi on either a standard enzyme-linked immunosorbent assay or immunoflourescence assay. We conclude that the presence of chronic Lyme disease cannot be excluded by the absence of antibodies against B. burgdorferi and that a specific T-cell blastogenic response to B. burgdorferi is evidence of infection in seronegative patients with clinical indications of chronic Lyme disease."
Dattwyler RJ; Volkman DJ; Luft BJ; Halperin JJ; Thomas J; Golightly MG. Seronegative Lyme disease. Dissociation of specific T- and B-lymphocyte responses to Borrelia burgdorferi.
the antigenic stimulus in Lyme arthritis would appear to be a small number of live spirochetes, demonstrated here by monoclonal antibodies, which may persist in the synovial lesion for years (p.494)".
Or as Dr. Steere, wrote in the New England Journal of Medicine (1990 Nov 22; 323(21):1438-44), "The likely reason for relapse is failure to eradicate the spirochete ... This last article is one of many studies that show continuing symptoms are most likely due to persistence of the spirochete [type of Lyme bacteria]." Indeed, many articles have been published before AND since 1990 demonstrating the possible persistence of Lyme infection in antibiotic-treated patients.
These studies have been written by members of the IDSA Lyme "team" and many other reputable scientists. And they are among the 98% of available literature on Lyme not cited in the IDSA’s newest treatment guidelines!

After reading the above links please prove lyme is cured in 21 days. Also how do you prove lyme is cured when the testing is about 85% innacurate.
See link below

Per IDSA / Gary Wormser, Only 9 Out Of 59 Were Steere IGG Positive. This Means 85% Of All Cases Will Be Missed By Using The Current CDC Criteria.
www.lymecryme.com

This link on lyme disease is a must see on www.lymecryme.com

BSL-4, or Biosafety Level 4, is the **highest** level of biosecurity in existence. It is reserved for the most dangerous pathogens known to mankind, generally transmissible by the airborne route. Click On The Binoculars And Type in Lyme Disease To See What The NIH Is Working With

Please see this link on www.lymecryme.com about death from Borrelia.
Remember death never happens from lyme disease

Section V1, Under Laboratory Hazards, Here Are Lab Acquired Infections From Borrelia Burgdorferi That They Stoped Working With In 1976. Borrelia Infections Were Passed In The Labs. Were They Working With Borrelia At The Time It was Breaking Out In CT? With 45 Cases And A Few Deaths From An Infection That Broke Out In 1975 And Was Not Named Till The Early 1980s. Also How Could Someone Die From Bb When They Tell Us It's As Mild As The Common Cold.

Having been the editor of a health related newspaper, and having worked with many doctors with their research and clinical experience with Lyme disease, I am just waiting for a main stream newspaper, or investigative reporter to jump on the opportunity of a lifetime and make this story known world wide.
This story is a Pulitzer opportunity if ever there was one!
Just as the story of the Tuskeegee Experiment broke in the 1970's, there is a story about Lyme disease waiting to be exposed.
If the IDSA, et al; camp is so convinced their research can stand the test of scrutiny and be upheld, why have they not given their emperical proof and claimed the $20,000 reward offered by www.lymecryme.com ? It is there for the taking for anyone who can PROVE with imperical evidence that 3-4 weeks of antibiotic treatment will CURE Lyme disease.
The IDSA has not made one step towards claiming that prize. One has to wonder WHY?
They know full well their research, if given that much scrutiny, would only result in criminal charges.
Where is the main stream journalist that will take this story by the horns and make history with the story that is absolutely Pulitzer material!
Dawn Irons, Editor
www.publichealthalert.org