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Jeff
Framingham, MA
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Redefined wrote: <quoted text> It seems Sickle Cell is also associated with homozygous & heterozygous which play a role in Human skin color. No it does not play any association with human skin color. I already went down the list of some of the alleles associated with human skin color. Sickle Cell has nothing to do with any of them, that is an adaptive eviromental autosomal marker and useless in tracing origins given it can't trace ancestry nor plays any part in phenotypes.
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Jeff
Natick, MA
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Barras Serrana wrote: But what are the genes that affect WHITE SKIN? You claim to be smart but you can't answer a simple question. <quoted text> You are obviously stupid because they were posted many times, dingleberry.
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Toomis
San Antonio, TX
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Bigsmoke wrote: <quoted text> Really? You're out of your depths here mate. At least study the subject before you go on making ludicrous claims which are prone to be shut down. Ha! Nope you are just an obfuscator, not really worth the time. Your alias reflects that. Bigsmoke as in big smoke screen. I'm not playing your go do your homework and come back bullshit. You just can't answer a simple question instead you lie about non Sub-Saharan HSS having any Neanderthal DNA. Your Ad lib shows how weak you are. Most likely one of those paid sockpuppets reading a script. Your adlib shows that you ignorant and not earning your dirty money. I guess you're pretty dumb. Try for a fastfood job because you fail at sockpuppetry. WOW, that's a pretty massive fail on your part. LOLz
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Jeff
Framingham, MA
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Bigsmoke wrote: <quoted text> Doesn't seem so otherwise they'd put it up there with rs1426654 (SLC24A5). Either way the argument would then go to; What was the time frame for its appearance? Considering the low frequency in South Asia who share common ancestry with Europeans between 40,000 - 10,000 years ago I believe that to be a reasonable time frame for when it arose. Methinks <20,000 years ago probably arising around the same time as rs1426654 (12,000 - 10,000 BP). This all still points to a darker people inhabiting early Europe. No it doesn't necessarily mean darker people were inhabiting early Europe because the Neanderthals were inhabiting early Eurasia before them and studies have shown they were fair complexion. http://www.google.com/imgres... http://www.sciencemag.org/content/318/5850/54... Europe is not the tropics, so early Eurasians having fair complexions dating back to 30,000 years ago wouldn't have been a shocker since their closest cousins, Neanderthals, had fair complexion and were inhabiting those same early Eurasia regions before them. Studies have shown rs1426654 (SLC24A5) is clearly associated with fair skinned among Europeans. Both rs1426654 (SLC24A5) and rs1426654 (SLC24A5) as well as Rs1042602 (TYRP1) are all associated with light skins in Europeans. "The two genes SLC24A5 and SLC45A2 were recently identified as major determinants of pigmentation in humans and in other vertebrates. The allele p.A111T in the former gene and the allele p.L374F in the latter gene are both nearly fixed in ---> LIGHT <---skinned Europeans, and can therefore be considered ancestry informative marker (AIMs). Here, we generate new allelic data for these two genes from samples of Chinese, Uygurs, Ghanaians, South African Xhosa, South African Europeans, and Sri Lankans (Tamils and Sinhalese). Our data confirm the earlier results and furthermore demonstrate that the SLC45A2 allele is a more specific AIM than the SLC24A5 allele because the former clearly distinguishes the Sri Lankans from the Europeans." http://www.ncbi.nlm.nih.gov/pubmed/16847698...
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Jeff
Framingham, MA
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Barras Serrana wrote: But they are not all white you idiot. Only northern euros are white. You lost this debate from page one. <quoted text> Wrong, you moron, Southern as well as Western and Eastern Europeans are as white as Northern Europeans. Geez, you are clueless.
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Jeff
Natick, MA
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Barras Serrana wrote: You have a link to prove this claim? Or am i suppose to take your word for it? <quoted text> Do you have accounts with sciencemag.org , www.ncbi.nlm.nih.go etc to be able to read ALL of the study, or are you like every other clueless idiot around here stupidly trying to understand what the study concludes based upon only the abstract says cause most of you are novices with no accounts to any of these scientific sites? </sarc>
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“There's enough for everyone”
Level 7
Since: Mar 07
USA
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Please wait...
Mmmm___BlackWomen wrote: Who gives a fcuk. Exactly
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Jeff
Framingham, MA
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Barras Serrana wrote: I do not know if you are aware of this. BUT NOT ALL EUROPEANS ARE WHITE SKINNED. Until you provide a link saying WHITE SKIN(not light skin) arose prior to 12k you will continue to look like an idiot. <quoted text> European are white, moron, and light skin means WHITE SKIN, you stupid fool. Look up the definition and ROOT for the word, means 'white'. Go learn English because it is very clearly English must be your second language.
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Jeff
Natick, MA
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Barras Serrana wrote: http://en.wikipedia.org/wiki/R ed_hair Estimates on the original occurrence of the currently active gene for red hair vary from 20,000 to 100,000 years ago.[27][28] It doesn't say anything about pale skin. <quoted text> The gene responsible for both pale skin and red hair dates back to before the time of the evolutionary separation of chimpanzees and humans, that's over millions of years ago. We know this to be true because the gene has also been found in chimps, as well as Neanderthals and Denisovans showing a common ancestry within the Hominidae tree. The LCA of Africans and non-Africans for the MC1R gene is about 1 mya. "A pigmentation gene from the bones of two Neandertals, reported online this week in Science, indicates that at least some Neandertals had pale skin and red hair, similar to some of the Homo sapiens who today inhabit their European homeland." http://www.sciencemag.org/content/318/5850/54...
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Barros Serrano
Reserve, NM
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Jeff wrote: <quoted text> No it doesn't necessarily mean darker people were inhabiting early Europe because the Neanderthals were inhabiting early Eurasia before them and studies have shown they were fair complexion. http://www.google.com/imgres... http://www.sciencemag.org/content/318/5850/54... Europe is not the tropics, so early Eurasians having fair complexions dating back to 30,000 years ago wouldn't have been a shocker since their closest cousins, Neanderthals, had fair complexion and were inhabiting those same early Eurasia regions before them. Studies have shown rs1426654 (SLC24A5) is clearly associated with fair skinned among Europeans. Both rs1426654 (SLC24A5) and rs1426654 (SLC24A5) as well as Rs1042602 (TYRP1) are all associated with light skins in Europeans. "The two genes SLC24A5 and SLC45A2 were recently identified as major determinants of pigmentation in humans and in other vertebrates. The allele p.A111T in the former gene and the allele p.L374F in the latter gene are both nearly fixed in ---> LIGHT <---skinned Europeans, and can therefore be considered ancestry informative marker (AIMs). Here, we generate new allelic data for these two genes from samples of Chinese, Uygurs, Ghanaians, South African Xhosa, South African Europeans, and Sri Lankans (Tamils and Sinhalese). Our data confirm the earlier results and furthermore demonstrate that the SLC45A2 allele is a more specific AIM than the SLC24A5 allele because the former clearly distinguishes the Sri Lankans from the Europeans." http://www.ncbi.nlm.nih.gov/pubmed/16847698... Naturally this means that the original inhabitants of the Maghreb 30,000 years ago also were light in color. Those Moors had NEVER been black! These halfwits should notice that people at the latitude of North Africa are not generally very dark... the dark people are near the equator. Wow there goes the black Inuit theory...
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Barras Serrana
Philadelphia, PA
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Jeff wrote: <quoted text> No it doesn't necessarily mean darker people were inhabiting early Europe because the Neanderthals were inhabiting early Eurasia before them and studies have shown they were fair complexion. This just proves your own agenda. Your own link clearly state only two neaderthals were tested. For all you know those could have been freaks of nature. From your own link: A pigmentation gene from the bones of ------>two Neandertals,<------ reported online this week in Science ( www.sciencemag.org/cgi/content/abstract/11474... ), indicates that at least ------->some Neandertals<------- had pale skin and red hair, similar to some of the Homo sapiens who today inhabit their European homeland.
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troll patrol
Philadelphia, PA
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Jeff wrote: <quoted text>
Europe is not the tropics, so early Eurasians having fair complexions dating back to 30,000 years ago wouldn't have been a shocker This just proves you do not know what their skin color was.
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Barros Serrano
Reserve, NM
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I've many times told these Afronazis about this stuff... that multiple genes affect skin color, that the genetic pathways to light skin are not the same among all peoples, that the red-hair allele in neandertal was not the same as the one in sapiens, that light color could be quite old, that adaptation of skin color has probably gone on for some time, that in fact the darkest people, such as W Africans, had evolved from prior lighter forms... Now Jeff produces the f'ing NUMBERS of the genes, all the details, and they still argue because they can't understand it! LOL... and they were claiming I was a liar and demanding sources. SMH... hopeless f'ing Afronazis. The only remedy is to slap the racism, ignorance and smartass out of them.
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soooooo
Chesterfield, VA
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Judged:
1
1
Jeff wrote: <quoted text> Wrong. Light skin evovled in humans soon after they migrated out of Africa.." That's complete horse shyt..it did not happen just because they fuycking left Africa..and white skin was put on cane for killing able.
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troll patrol
Philadelphia, PA
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Jeff wrote: <quoted text> Rs16891982 (p.L374F MATP) IS NOT for "Light Brown" skin, stupid, but for FAIR complexion. Its typically associated in Europeans with dark hair and light aka 'WHITE' skin. This doesn't prove anything. Just cause the gene is fixed to euros now doesn't mean they are the only ones that posess that gene. You said youself it is TYPICALLY associated in europeans with dark hair and white skin. That right there means they are not the only ones that have that gene.
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troll patrol
Philadelphia, PA
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Jeff wrote: <quoted text> European are white, moron, and light skin means WHITE SKIN, you stupid fool. Look up the definition and ROOT for the word, means 'white'. Go learn English because it is very clearly English must be your second language. There you go again with your stupidity. Not all euros have white skin you fool. Many have OLIVE skin which is NOT white/pale skin. You thinking all euros have white skin shows you either have an agenda or you are just stupid.
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troll patrol
Philadelphia, PA
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Judged:
1
1
Jeff wrote: <quoted text> The gene responsible for both pale skin and red hair dates back to before the time of the evolutionary separation of chimpanzees and humans, that's over millions of years ago. We know this to be true because the gene has also been found in chimps, as well as Neanderthals and Denisovans showing a common ancestry That still does not prove modern "eurasians" were white skinned.
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troll patrol
Philadelphia, PA
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Barros Serrano wrote: I've many times told these Afronazis about this stuff... that multiple genes affect skin color, that the genetic pathways to light skin are not the same among all peoples, that the red-hair allele in neandertal was not the same as the one in sapiens, that light color could be quite old, that adaptation of skin color has probably gone on for some time, that in fact the darkest people, such as W Africans, had evolved from prior lighter forms... Now Jeff produces the f'ing NUMBERS of the genes, all the details, and they still argue because they can't understand it! LOL... and they were claiming I was a liar and demanding sources. SMH... hopeless f'ing Afronazis. The only remedy is to slap the racism, ignorance and smartass out of them. He has not proven anything either way. He himself has stated the modern "eurasians" may have has white skin because he does not know.
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Jeff
Framingham, MA
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Barras Serrana wrote: <quoted text> This just proves your own agenda. Your own link clearly state only two neaderthals were tested. For all you know those could have been freaks of nature. From your own link: A pigmentation gene from the bones of ------>two Neandertals,<------ reported online this week in Science ( www.sciencemag.org/cgi/content/abstract/11474... ), indicates that at least ------->some Neandertals<------- had pale skin and red hair, similar to some of the Homo sapiens who today inhabit their European homeland. Two Neandertals having the Mc1r gene means others had it too, which means that if it existed in those two then the gene existed in others too, and we know others did have it because this gene is also found in modern humans as well as chimps and Denisovans. lol! You really don't know how genetics works, do you. lol! "The findings, published this week in Science1, are based on the sequence of a single gene, called mc1r. Humans with a less functional form of the MC1R protein are more likely to be fair skinned — an adaptation that may have helped inhabitants of high latitudes synthesize vitamin D more efficiently in limited sunlight." http://www.nature.com/news/2007/071025/full/n...
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Jeff
Framingham, MA
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troll patrol wrote: <quoted text> This just proves you do not know what their skin color was. It wasn't black because there is evidence of their very close homospecies cousins living in the region long before they did and there were among them fair complexion types. lol
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