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Sulfasalazine (generic), Azulfidine

May 10, 2008

Sulfasalazine for rheumatoid arthritis may cause severe hepatotoxicity

“Serious hepatotoxicity, often associated with a skin rash and variably associated with evidence of an allergic reaction on blood tests - eosinophilia -- occurs within 6 weeks of starting sulfasalazine”

Potentially fatal hepatotoxicity can be triggered by sulfasalazine therapy for rheumatoid arthritis, according to a series of case reports investigated by UK researchers. via Rehab Management

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