Prevacid, Lansoprazole News

Children with asthma who don't have heartburn and other signs of gastroesophageal reflux don't get additional asthma control from acid-reducing medications, according to new research.

The U.S. Food and Drug Administration announced a safety alert for proton pump inhibitors .

An acid reflux drug frequently prescribed for children with poorly controlled asthma does not improve asthma control if the child has no symptoms of acid reflux, according to a recent study published in JAMA: the Journal of the American Medical Association .

The U.S. Food and Drug Administration said Tuesday that certain stomach-acid medications known as proton-pump inhibitors, or PPIs, can trigger the development of Clostridium difficile-associated diarrhea, a bacterial infection that can be particularly hazardous to the elderly.

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Physicians often prescribe the acid reflux drug lansoprazole in addition to standard inhaled steroid drugs to children who have asthma.

Physicians often prescribe the acid reflux drug lansoprazole in addition to standard inhaled steroid drugs to children who have asthma.

Doctors often prescribe drugs called PPIs for people with asthma. These medications treat stomach-acid reflux.

Use of a proton-pump inhibitor in children with poorly controlled asthma does not improve their symptoms, according to a JAMA study.

Asymptomatic gastroesophageal reflux is prevalent in children with asthma, and untreated GER has been postulated as a cause of poor asthma control.

Lansoprazole therapy slightly increased the risk of sore throats and other respiratory problems in children, however.

Authors/Writing Committee: The following investigators of the American Lung Association Asthma Clinical Research Centers take authorship responsibility for the study results: Janet T. Holbrook, MPH, PhD, Center for Clinical Trials, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Robert A. Wise, MD, Johns Hopkins University ... (more)

Children without symptoms of gastroesophageal reflux whose asthma was being poorly controlled with anti-inflammatory treatment did not have an improvement in symptoms or lung function with the added treatment of the proton pump inhibitor lansoprazole, compared to patients who received placebo, according to a study in the January 25 issue of JAMA .