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Changes in use of valproate and other mood stabilizers for patients...
NEW edkay potential Abstract OBJECTIVE: The study describes changes over time in the adjunctive use of valproate and other mood stabilizers-lithium, carbamazepine, and gabapentin--among hospitalized psychiatric patients with a diagnosis of schizophrenia.
Updated June 15, 2006 Pregabalin A newly approved oral drug for treating neuropathic pain from diabetic peripheral neuropathy.
DepoMed: Protected by Cash and Headed Higher
DepoMed's two Phase III trials for vasomotor symptoms ended in March 2009 and April 2009.
XenoPort's Solzira a Potential Blockbuster
We consider XenoPort's XP-13512 -- a gabapentin pro-drug, to be called Solzira in the U.S. -- to be a potential blockbuster opportunity with a full label to include restless leg syndrome , neuropathic pain , and migraine prophylaxis.
The antiepileptic agent gabapentin (Neurontin) possesses...
Gabapentin displayed anxiolytic-like action in the rat conflict test, the mouse light/dark box and the rat elevated X-maze with respective minimum effective doses of 3, 10 and 30 mg/kg. Furthermore, gabapentin also induced behavioural changes suggestive of anxiolysis in the marmoset human threat test with a MED of 30 mg/kg. In the rat formalin test ...
DRUG NEWS POSTHERPETIC NEURALGIA Oxycodone eases acute shingles pain Although patients with herpes zoster can suffer severe acute pain for several weeks, little research has been done on effective oral treatments.
Fringe #1 - #3: A Medical Review
In addition to watching the television show Fringe , I also read the Fringe comic published by WildStorm.
Mayo Clinic researchers say agent provides treatment option for women with hot flashes
A pill used for nerve pain offers women relief from hot flashes, Mayo Clinic researchers report at the 45th Annual Meeting of the American Society of Clinical Oncology .
Pfizer Again Beats Back Class Certification Motion in Consumer Fraud Case
Shortly after Pfizer predecessor Warner-Lambert pleaded guilty and agreed to pay more than $430 million to resolve criminal charges and civil liabilities for promoting off-label uses for its epilepsy drug Neurontin in 2004, plaintiffs lawyers were in court seeking to represent a nationwide class of consumers and third-party payers against the ...
FDA mandates drug label revisions, black box warnings
The Food and Drug Administration has issued new labeling requirements for anti-seizure drugs due to potential increased risk of suicidal behaviors, according to FDA MedWatch .
Phase II Results for GSK1838262 (XP13512) Reported for Neuropathic...
Phase II Results for GSK1838262 Reported for Neuropathic Pain Associated with Diabetic Peripheral Neuropathy RESEARCH TRIANGLE PARK, N.C. & SANTA CLARA, Calif.-- --Apr 27, 2009 - GlaxoSmithKline and XenoPort , Inc.
FDA Reviews Solzira; XenoPort Exercises Co-Promote Option
While the FDA reviews a new drug application for Solzira in restless legs syndrome, XenoPort Inc.
XenoPort Announces Election of Co-Promotion Option for Solziraa
XenoPort, Inc. announced today that it has exercised the option contained in its Development and Commercialization Agreement with GlaxoSmithKline to co-promote and share profits and losses from the potential future sales of Solzira Extended Release Tablets in the United States.
Oxycodone Effective Against Shingles Pain
The painkiller oxycodone is effective at treating the acute pain of shingles, an illness that often causes severe pain which can become long-lasting and sometimes even permanent.
Ask Dr. Gott: WWII vet fights peripheral neuropathy
Dear Dr. Gott: I am a 90-year-old veteran of World War II and have had peripheral neuropathy for several years.
Veteran fights peripheral neuropathy
DEAR DR. GOTT: I am a 90-year-old veteran of the Second World War and have had peripheral neuropathy for several years.
New guidelines help doctors diagnose elusive nerve problem called neuropathy
A painful form of the nerve problem known as neuropathy left Millie Murphy unable to walk on her own and unable to tolerate shoes, socks or even a bed sheet on her right foot.
Do You Have Fibromyalgia? Drug Company Hopes So.
Even as new reports surface about fake medical articles Pfizer planted to sell seizure drug Neurontin for unapproved uses from 1995 to 2002, it looks like deja vu all over again.
Thriving In The Throes Of A Downturn: Pop a pill to beat the blues
WHEN times are bad, turn to Viagra. Pharmacists are reporting a spike in Viagra sales as harder times bite.
Judge Decertifies Class Action Over Off-Label Use of Epilepsy Drug
A month before a pharmaceutical class action was set for trial, a Philadelphia judge decertified the class of users of an epilepsy and neuralgia drug seeking reimbursement from the drug's maker after being ...