Sunday Jul 6 | Seeking Alpha
Barr and Mylan Invalidate Boehringer Ingelheim's Patent on Mirapex
A week ago, following a bench trial held in March, the U.S. District Court for the District of Delaware held that Boehringer Ingelheim's patent on Mirapex is invalid for obviousness-type double patenting.
RLS medication loses efficacy over time
People with restless legs syndrome are sometimes prescribed Parkinson's disease drugs to treat what they describe as an irresistible urge to move their legs, especially at night.
Generic Erosion of Market Leading Therapies Will Constrain Growth in...
The new Pharmacor report entitled Parkinson's Disease finds that the generic erosion of Boehringer Ingelheim's Mirapex/Mirapexin/Sifrol, GlaxoSmithKline's Requip, Teva/Lundbeck's Agilect/Azilect and ...
Pramipexole (Mirapexin(R)/Sifrol(R)) Can Significantly Reduce Limb...
Main Category: Pain / Anesthetics Also Included In: Neurology / Neuroscience Article Date: 10 Jun 2008 - 2:00 PDT A new study demonstrating that pramipexole /Sifrol ) can significantly reduce RLS-associated ...
Parkinson's drug listed on PBS
The listing of a Parkinson's drug on the Pharmaceutical Benefits Scheme , which previously cost up to $15,000 a year, has opened a new chapter of treatment for sufferers of the disease.
Drugs for Restless Legs Syndrome Have Downsides
“If you are concerned about safety, ropinerole had a higher rate of withdrawal.”
The drugs that are widely used to treat restless legs syndrome do provide relief, but they are burdened by side effects and a gradual loss of effectiveness that causes many sufferers to stop taking them, a new ... via HON
New Data Confirm Pramipexole (Mirapexin(R)/Sifrol(R)) Can...
The important finding, presented today at the 60th Annual Meeting of the American Academy of Neurology in Chicago, U.S.A., highlights the benefit of an RLS treatment which effectively targets the core symptoms ... via Earth Times
Knopp Neurosciences Initiates Phase 2 Study Of KNS-760704 In Amyotrophic Lateral Sclerosis
“This step represents another important milestone for Knopp in our efforts to develop an effective treatment for this relentless disease.”
Main Category: Muscular Dystrophy / ALS Also Included In: Clinical Trials / Drug Trials Article Date: 10 Apr 2008 Knopp Neurosciences Inc. via MediLexicon
Fresh hope: Drug shows promise for ALS sufferers
“If you have ALS, you're going to die, period.”
In 2004, a small and desperate group of terminally ill patients pleaded with UVA hospital not to pull the plug on an experimental drug they claimed could be their only hope. via The Hook
Widely advertised - restless legs' drugs move into court
“When your legs feel better, you feel better.”
The television advertisements for Mirapex show a stick figure, whose legs have annoying sensations that keep it up at night-sensations like "lightning legs," "pins and needles," "creepy crawlies," and "the urge ... via Trial
Knopp Neurosciences Completes First Series B Financing of $10 Million
“Our funding arrangements will meet our capital requirements so long as we continue to achieve the milestones we established with our investors in advance”
Jan 22, 2008 - Knopp Neurosciences Inc. said it completed a Series B funding round of $10 million, increasing its total capitalization to $20 million. via Med Ad News
NLH Question Answering Service
What is the latest available evidence on drug treatment for idiopathic restless leg syndrome?
GPNotebook states in its entry on restless leg syndrome: "Restless legs syndrome is idiopathic in most patients..." [1] TRIP has recently produced an evidence-based review on the management of restless legs ... via NLH Question Answering Service
Knopp Neurosciences Presents Results Of Phase 1 Ascending Single-Dose Study Of KNS-760704
“We are encouraged that based on this study, KNS-760704 may enable neuroprotective dose levels to be rapidly achieved without the need for titration”
Main Category: Muscular Dystrophy / ALS News Article Date: 05 Dec 2007 - 4:00 PST newsletters Knopp Neurosciences Inc. via Medical News Today
Barr Receives Tentative Approval For A Generic Version Of Mirapex(R)...
Barr Pharmaceuticals, Inc. announced that its subsidiary, Barr Laboratories, Inc., has received tentative approval from the U.S. Food and Drug Administration for its generic version of Boehringer Ingelheim ... via MediLexicon
CORRESPONDENCE: Peripheral Edema and Dopamine Agonists in Parkinson Disease
I read with interest the article by Kleiner-Fisman and Fisman1 where they highlighted a 16% prevalence of peripheral edema presumably induced by pramipexole in patients with Parkinson disease . via Archives General Psychiatry