Avandia, Rosiglitazone News

Updated June 15, 2006 PPAR Agonists A family of drugs that activate certain proteins in the body called peroxisome proliferator-activated receptors .

The Food and Drug Administration said Tuesday that drugs containing propoxyphene, a strong pain-killing ingredient that carries a risk of accidental overdose, may stay on the market but their labels must show a boxed warning of the risks, the Associated Press reports .

THE USE OF THIAZOLIDINEDIONES to treat type 2 diabetes has been associated with an increased risk of bone fracture.

For the 200 million diabetics worldwide, the past few years have brought some disturbing findings about risks that may be associated with certain diabetes drugs.

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In a blow to the diabetes treatment franchise of a Deerfield drug maker, the U.S. Food and Drug Administration has asked Takeda Pharmaceuticals North America Inc.

London, June 23 : A new study may help explain how a class of diabetes drugs increases the risk of heart failure.

Alun Jones, MBBS * ; Rajdeep Deb, MBBS * ; Evelyn Torsney, PhD ; Franklyn Howe, PhD ; Mathew Dunkley, MBBS, PhD ; Yanosha Gnaneswaran, MRes ; David Gaze, PhD ; Hosaam Nasr, MBBS ; Ian M. Loftus, MD, FRCS ; Mathew M. Thompson, MD, FRCS ; Gillian W. Cockerill, PhD From the Department of Cardiovascular Sciences, St George's University of London, ...

"GW Metabolic Research Laboratory" established in conjunction with Professor Cawthorne and the Clore Laboratory, University of Buckingham Porton Down, UK, 16 June 2009: GW Pharmaceuticals plc announces that it has entered into an exclusive strategic alliance with Professor Mike Cawthorne and the Clore Laboratory, University of Buckingham, focusing ...

A class of oral diabetes drugs, commonly nicknamed "glitazones." Unlike the traditional oral drugs called sulfonylureas , which lower blood glucose levels by making the pancreas secrete more insulin, the thiazolidinediones work by helping the body's tissues to use insulin more effectively and by suppressing glucose production by the liver.

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VeroScience, in collaboration with S2 Therapeutics, announced the presentation of clinical and preclinical data at the American Diabetes Association 69th Scientific Sessions on Cycloset, a novel treatment for patients with Type 2 diabetes.

Taking the diabetes medications metformin and rosiglitazone together reverses the adverse effects on bone of rosiglitazone treatment alone in an experimental model, according to a new study done in rats.

Zurich-based drug maker Roche Holding said today it will perform late-stage testing on a potential blockbuster diabetes drug.

June 8, 2009 -- For people with diabetes and stable heart disease , drug therapy works just as well as immediate bypass surgery or angioplasty to open clogged arteries , a study suggests.

The results from the phase II SYNCHRONY study are published in an article Online First and in a future edition of The Lancet .

Strict lowering of blood sugar may not have been the cause of excess deaths in a major study of patients with type 2 diabetes, U.S. researchers said on Tuesday.

Ian M. Loftus MD, FRCS, Mathew M. Thompson MD, FRCS, and Gillian W. Cockerill PhD* From the Department of Cardiovascular Sciences, St George's University of London, Cranmer Terrace, London, UK.

All study participants were stable enough not to need surgery immediately. For people with Type 2 diabetes and stable heart disease, drug treatments are as effective as angioplasty or bypass surgery in some cases, a new study suggests.

Patients with heart failure and those at risk for fractures shouldn't use Avandia, says study author Philip Home, however "when used in appropriately selected patients, [Avandia] carries no overall increase in cardiovascular risk." Photo illustration by Justin Sullivan, Getty Images FACTS ABOUT DIABETES * Nearly 24 million Americans have diabetes.