Avandia, Rosiglitazone News

OBJECTIVE Study the effects of exenatide plus rosiglitazone on I2-cell function and insulin sensitivity using hyperglycemic and euglycemic insulin clamp techniques in participants with type 2 diabetes on metformin.RESEARCH DESIGN AND METHODS In this 20-week, randomized, open-label, multicenter study, participants continued their metformin regimen ... (more)

GlaxoSmithKline Plc, the U.K.'s largest drugmaker, reported fourth-quarter sales that missed analysts' estimates and announced a smaller share repurchasing program than last year.

In recognition of American Heart Month, LawyersandSettlements.com, the premier publication for Online Legal Media, today released its Top 10 list of prescription drug lawsuit topics in which heart attack or heart side effects were the alleged primary injuries.

GlaxoSmithKline Plc , which is paying $3 billion to resolve government claims that it illegally marketed drugs such as the Avandia diabetes medication, agreed to settle more lawsuits over the pills, a lawyer said.

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Federal health regulators have approved Amylin Pharmaceutical's long-delayed diabetes drug Bydureon, a next-generation treatment that requires fewer injections than the company's current offering, Byetta.

The Food and Drug Administration approval comes after two previous rejections in 2010, when the agency asked Amylin to conduct a new study of the drug's effects on the heart.

Bristol-Myers Squibb Co. and AstraZeneca Plc failed to win U.S. clearance to sell the first in a new class of experimental diabetes pills as regulators sought more data on the medicine's safety.

Researchers have broken down the way in which the U.S. Food and Drug Administration notifies the general public and health care providers about unanticipated risks from approved medications into four different categories: warnings about serious harmful events, recommendations against use in certain patient populations, averting harmful drug-drug ... (more)